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Equine
Gastric Ulcer Syndrome (EGUS)
Horses, like humans, can
suffer from ‘gastric ulcers’. These erosions in the
wall of the stomach are caused literally by the stomach digesting
itself. It was only with the advent of endoscopes long enough
to reach into the stomach of a horse (3 meters!) that the real
prevalence of this condition became apparent. Studies since have
shown that up to 60% of sport horses and 90% of racehorses in
training have gastric ulcers. Left untreated they can cause a
variety of signs from poor performance to recurrent colic.
What Causes Equine Gastric ulcer syndrome?
The content of a horse’s
stomach is pretty nasty. It is very acidic and contains enzymes
which digest proteins. To protect itself against being burnt and
digested the lining of the stomach produces a mucus lining. Saliva
swallowed from the mouth also helps neutralise the acid. Ulcers
occur when the acid stomach contents overwhelm these protective
factors.
What are the risk factors for horses to develop EGUS?
1) Diet:
Horses naturally eat little and often. This allows a steady production
of digestive juices in their stomach and of saliva in their mouths,
which neutralises the acidic stomach. Concentrates require less
chewing than forage and therefore cause less neutralising saliva
to be produced, increasing the acidity in the stomach.
2) Exercise:
The horse’s stomach lining is divided into 2 distinct areas.
The lower part is tougher, and has cells, which produce protective
mucus. Because it is lower, it is normally submerged by the acidic
food. The lining of the upper part of the stomach is more susceptible
to ulceration. Normally it is not in contact with the acidic food.
However when the horse is exercised this splashes the contents
onto the upper lining, increasing the chance of ulceration. Horses
in high levels of work are more likely to develop ulcers.
3) Stress or illness
Both these will reduce the blood flow to the stomach, weakening
its defence against the acid.
4) Drug therapy
Non steroidal anti inflammatory drugs (NSAIDs) such as phenylbutazone
(‘Bute’) can decrease production of prostaglandins,
a hormone which helps protect the stomach against ulcers.
What signs might
my horse show with gastric ulcers?
Foals are far more susceptible
and show much worse signs. They may salivate profusely, grind
their teeth and develop colic and diarrhoea.
In adult horses the signs are usually more subtle. Weight loss,
poor performance, decreased appetite, dullness, recurrent colic
and wind sucking are often seen, although sometimes they show
no signs at all.
How can you diagnose EGUS?
Initially, your vet might
be suspicious if your horse shows the signs above. However, examining
the lining of the stomach with a gastroscope can only make a definitive
diagnosis.
How do you
treat EGUS?
There are several ways to
treat EGUS.
1) Omeprazole (Gastrogard) is normally the drug of choice. It
works by inhibiting the production of acid from the lining of
the stomach, and is given for at least 2 - 4 weeks.
2) Feed low concentrate, high fibre diets (especially alfalfa).
3) Reduce intensity of training.
4) Reduce stress. Minimise travelling or box confinement.
5) Further drug treatment. There are several other drugs, which
may be used to treat EGUS, according to its severity and response
to initial treatment.
Ulcers normally take 2-4 weeks to heal, and normally the horse
will be rescoped to check progress at this time
Gastric ulcers
seen via a videoendoscope.
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