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The
Liphook Equine Hospital
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) or RECURRENT
AIRWAY OBSTRUCTION (RAO).
COPD is a relatively
common cause of coughing and nasal discharge in stabled
horses. A more appropriate name for the condition which
is becoming used more frequently is "recurrent airway
obstruction" (RAO). In long standing cases the horse
may have difficulty in breathing and its chest and abdomen
can be easily seen to move, hence the old name ‘heaves’.
What is COPD ?
COPD is a disease of
the smaller airways (bronchioles and alveoli) in the lungs
caused by an allergy to small dust particles and spores
which are inhaled by the horse when he breaths. Fungal spores
and/or pollen dust are most important in terms of allergic
‘trigger’ factors. The allergic reaction in
the airways results in the production of fluid and thickening
and spasm of the walls of the small airways of the lungs,
causing their obstruction. This means that the horse has
to make an increased effort to breath and he develops a
cough to clear trapped mucus. The pathology which occurs
in the horse’s lungs is usually reversible except
in very severe cases. Affected horses will usually react
to dusts throughout their entire life - hence the condition
cannot be ‘cured’ but the progress of the disease
can be halted and the horse can be helped to accommodate
to it.
What are the symptoms
of COPD?
In early cases, the
only clinical sign may be poor exercise tolerance, a slight
nasal discharge or dry cough which may go unnoticed. If
untreated, the horse may start to find faster work more
difficult. The cough will become more noticeable. As the
disease progresses, the horse will cough with only slight
exercise. In severe cases, the horse will have difficulty
breathing even at rest, causing increased respiratory rate
and effort. In very long standing cases, the horse has to
make a double effort to breath out, using both the chest
and abdominal muscles, developing a noticeable ‘heave
line’. These horses used to be called ‘broken
winded’.
Symptoms often progress
slowly with age. In some horses, however, acute attacks
of respiratory distress accompany a repeated exposure to
dust or pollens. This means that the condition may be seasonal
(especially when associated with crops such as oil seed
rape) or associated with stabling or feeding conditions.
Summertime associated problems are becoming very frequent
nowadays.
What causes COPD to
develop and how is it diagnosed?
For a horse to show
signs of COPD, he must have developed an allergy to inhaled
dust, spores or pollen. A horse may be allergic to pollen
but not spores or visa versa. Fungal spores are present
in hay and straw, mouldy bedding or feed, and other organic
material. Pollens are found just about everywhere but levels
in the air fluctuate greatly with season, location and weather
conditions. As with human hay fever, the higher the pollen
count in the air, the worse the condition becomes. Air quality
in stables is therefore important for continuing equine
health.
The diagnosis of COPD
is based on history, management conditions and clinical
signs. Endoscopy (‘scoping’) and the collection
of samples for microscopic examinations (tracheal washes
and bronchoalveolar lavages, or BALs) helps to distinguish
between COPD and other causes of chronic cough such as infection.
Infection may, of course, be a secondary complication of
COPD and also COPD may apparently be triggered by infections
such as viruses.
What treatments are
available?
It is important to
remember that COPD is an allergic problem. The fundamental
basis to treating allergies is clearly to avoid contact
with the trigger factor(s). Many early stage cases respond
well simply to changes in management which remove the cause
of the allergy. Horses with COPD should be kept on ‘dust-free’
management, designed to keep environmental dust and spore
levels as low as possible. Bedding should be paper, shavings
or other non-organic material and should be kept scrupulously
clean. Hay should be soaked for at least 30 minutes before
being fed or preferably haylage should be used. ‘Dry’
feed should be fed dampened to reduce dust. Horses should
be stabled away from other horses bedded on straw and away
from hay and straw stores, muck heaps and other sites where
dust and moulds may be produced. The need for good air quality
and efficient ventilation cannot be over emphasised. Horses
affected out of doors by pollens should be moved from high
pollen areas until the season has passed. Clearly summertime
pollen associated allergies are far more problematic to
control as avoidance of the cause may often be impossible.
More severe or long
standing cases often require medication. Medicines which
dilate the airways (bronchodilators) such as clenbuterol
may be given or corticosteroids can be used to reduce the
allergic reaction.
These medicines may
be given by mouth, by injection or by inhalation. The advantage
of inhalation therapy is that the medication is delivered
straight to the lungs so the effect can be quicker and lower
dosages of medicine may be used. Many cases require long
term treatment (especially summertime problems).
Best Advice
Good management is
the key to owning a horse with COPD. Maintaining a clean,
dust-free, well-ventilated environment, correct storage
and maintenance of feeds and bedding and the use of hypoallergenic
bedding materials all help reduce the incidence and the
severity of this chronically-incapacitating condition.
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